Meningioma: Difference between revisions

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= Meningioma Grades =
= Diagnosis =
== Imaging findings ==
* Wide dural based
* Hyperostosis
* Dural tail
* Calcifications
* Homogeneous enhancement 
* Pneumosinus dilatans
* MRI: isointense on T1WI, hypointense on T2WI
 
== Histopathology ==
[[File:Meningioma - Histopathology .jpg|thumb|500x500px]]
* The tumour cells have features of both syncytial and fibroblastic type forming <mark>whorls</mark> which contain central laminated areas of calcification called <mark>psammoma bodies</mark>.
<br clear="all">
=== Meningioma Grades ===
{| class="wikitable" style="width:100%;"
{| class="wikitable" style="width:100%;"
! GRADE I
! GRADE I
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* Anaplastic (malignant) meningioma
* Anaplastic (malignant) meningioma
|}
|}
= Diagnosis =
== Imaging findings ==
* Wide dural based
* Hyperostosis
* Dural tail
* Calcifications
* Homogeneous enhancement 
* Pneumosinus dilatans
* MRI: isointense on T1WI, hypointense on T2WI
== Histopathology ==
[[File:Meningioma - Histopathology .jpg|thumb|500x500px]]
* The tumour cells have features of both syncytial and fibroblastic type forming <mark>whorls</mark> which contain central laminated areas of calcification called <mark>psammoma bodies</mark>.
<br clear="all">
=== Meningioma Grades ===
==== GRADE I ====


== Immunohistochemical staining ==
== Immunohistochemical staining ==

Latest revision as of 22:57, 4 March 2024

General information

  • Meningiomas are a group of tumors that are believed to originate in meningothelial cells of the arachnoid membrane.
  • They may be intracranial (MC), intraorbital, or intra-spinal.



Diagnosis

Imaging findings

  • Wide dural based
  • Hyperostosis
  • Dural tail
  • Calcifications
  • Homogeneous enhancement
  • Pneumosinus dilatans
  • MRI: isointense on T1WI, hypointense on T2WI

Histopathology

  • The tumour cells have features of both syncytial and fibroblastic type forming whorls which contain central laminated areas of calcification called psammoma bodies.


Meningioma Grades

GRADE I GRADE II GRADE III
  • Meningothelial meningioma
  • Fibrous meningioma
  • Transitional meningioma
  • Psammomatous meningioma
  • Angiomatous meningioma
  • Microcystic meningioma
  • Secretory meningioma
  • Lymphoplasmacyte-rich meningioma
  • Metaplastic meningioma
  • Atypical meningioma
  • Clear cell meningioma
  • Chordoid meningioma
  • Rhabdoid meningioma
  • Papillary meningioma
  • Anaplastic (malignant) meningioma

Immunohistochemical staining

  • EMA ⊕ in ~80%