Intracranial pressure (ICP): Difference between revisions

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*Normal ICP: <10-15 mmHg, varies w/ age, position, straining, & coughing
*Normal ICP: <10-15 mmHg, varies w/ age, position, straining, & coughing
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== Monro-Kellie doctrine ==
== Monro-Kellie doctrine ==
* ↑ in vol. of one intracranial compartment → ↑ ICP unless offset by ↓ vol. in another compartment
* ↑ in vol. of one intracranial compartment → ↑ ICP unless offset by ↓ vol. in another compartment
* Brain parenchyma predominantly incompressible fluid, CBV & CSF key in buffering additional intracranial volume by ↑ venous outflow/↓ CBF, displacing/↓ intracranial [[CSF]]
* Brain parenchyma predominantly incompressible fluid, CBV & CSF key in buffering additional intracranial volume by ↑ venous outflow/↓ [[CBF]], displacing/↓ intracranial [[CSF]]
* Infants have extra volume compensation w/ open fontanelle
* Infants have extra volume compensation w/ open fontanelle
* Pathologic processes can easily ↑ ICP by exceeding compensatory capacity due to small size of CBV & CSF compartments
* Pathologic processes can easily ↑ ICP by exceeding compensatory capacity due to small size of CBV & CSF compartments
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*formation of cerebrospinal fluid (If)
*formation of cerebrospinal fluid (If)
*sagittal sinus pressure (PSS)
*sagittal sinus pressure (PSS)
<hr>
= ICP monitoring =
== Purpose of ICP monitoring ==
# Early warning
# Goal directed Tx
== Indications (BTF) ==
# abnml CT
# GCS <9
# Hx of TBI
[[Category:Neurophysiology]]
[[Category:Neurophysiology]]
[[Category:Neurotrauma]]
[[Category:Neurotrauma]]

Latest revision as of 05:26, 22 November 2024

  • Normal ICP: <10-15 mmHg, varies w/ age, position, straining, & coughing

ICP & intracranial volume

  • Brain parenchyma: 1400 ml (80% total, 10% solid, 70% tissue water)
  • CBV: 150 ml (10% total)
  • CSF: 150 ml (10% total) (tot. ~1700 ml)

Monro-Kellie doctrine

  • ↑ in vol. of one intracranial compartment → ↑ ICP unless offset by ↓ vol. in another compartment
  • Brain parenchyma predominantly incompressible fluid, CBV & CSF key in buffering additional intracranial volume by ↑ venous outflow/↓ CBF, displacing/↓ intracranial CSF
  • Infants have extra volume compensation w/ open fontanelle
  • Pathologic processes can easily ↑ ICP by exceeding compensatory capacity due to small size of CBV & CSF compartments

Pressure-Volume curve

  • Additional intracranial volume initially accommodated w/ little/no Δ ICP (flat part of curve)
  • Once craniospinal buffering capacity exhausted (decompensation point), small ↑ in intracranial vol. → substantial ↑ ICP

Davson equation

ICP = If * Rout - PSS

  • resistance to cerebrospinal fluid outflow (Rout)
  • formation of cerebrospinal fluid (If)
  • sagittal sinus pressure (PSS)



ICP monitoring

Purpose of ICP monitoring

  1. Early warning
  2. Goal directed Tx

Indications (BTF)

  1. abnml CT
  2. GCS <9
  3. Hx of TBI