Esthesioneuroblastoma: Difference between revisions
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(Created page with "{{NoteBox|warn}}= KEY CONCEPTS = * Esthesioneuroblastoma (ENB) is an uncommon neoplasm arising from the olfactory epithelium high in the nasal vault, which frequently invades the skull base, orbit, and cranial vault. * Both the Hyams histologic grading system and Kadish staging stratification have prognostic value with respect to outcomes in patients with ENB. * Surgery remains the mainstay of treatment with a goal of negative margins. Surgical techniques were traditiona...") |
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{{NoteBox|warn}} | {{NoteBox|warn}}<h1>KEY CONCEPTS</h1> | ||
* Esthesioneuroblastoma (ENB) is an uncommon neoplasm arising from the olfactory epithelium high in the nasal vault, which frequently invades the [[Skull Base|skull base]], orbit, and cranial vault. | * Esthesioneuroblastoma (ENB) is an uncommon neoplasm arising from the olfactory epithelium high in the nasal vault, which frequently invades the [[Skull Base|skull base]], orbit, and cranial vault. | ||
* Both the Hyams histologic grading system and Kadish staging stratification have prognostic value with respect to outcomes in patients with ENB. | * Both the Hyams histologic grading system and Kadish staging stratification have prognostic value with respect to outcomes in patients with ENB. | ||
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* Radiotherapy is commonly used postoperatively. Preoperative radiotherapy has been used with benefit in advanced-stage ENB, and chemotherapy is also often used. | * Radiotherapy is commonly used postoperatively. Preoperative radiotherapy has been used with benefit in advanced-stage ENB, and chemotherapy is also often used. | ||
* Radiosurgery has been effectively used for residual or recurrent tumors of limited size.{{NoteBoxEnd}} | * Radiosurgery has been effectively used for residual or recurrent tumors of limited size.{{NoteBoxEnd}} | ||
[[Category:Neuro-Oncology]] | |||
Latest revision as of 23:05, 2 March 2024
KEY CONCEPTS
- Esthesioneuroblastoma (ENB) is an uncommon neoplasm arising from the olfactory epithelium high in the nasal vault, which frequently invades the skull base, orbit, and cranial vault.
- Both the Hyams histologic grading system and Kadish staging stratification have prognostic value with respect to outcomes in patients with ENB.
- Surgery remains the mainstay of treatment with a goal of negative margins. Surgical techniques were traditionally craniofacial approaches, with the addition of endoscopic techniques recently.
- Radiotherapy is commonly used postoperatively. Preoperative radiotherapy has been used with benefit in advanced-stage ENB, and chemotherapy is also often used.
- Radiosurgery has been effectively used for residual or recurrent tumors of limited size.