Meningioma: Difference between revisions

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{{NoteBox|secondary}}<strong>Related pages</strong>
{{NoteBox|secondary}}<strong>Related pages</strong>
* [[cavernous sinus meningioma|Cavernous sinus Meningiomas]]{{NoteBoxEnd}}
* [[Anterior skull base Meningiomas]]
* [[cavernous sinus meningioma|Cavernous sinus Meningiomas]]
* [[Parasagittal and falx meningiomas]]{{NoteBoxEnd}}
[[File:BT SupTentPostFossa OlfGrve 02.jpg|thumb|454x454px]]
= General information =
* Meningiomas are a group of tumors that are believed to originate in meningothelial cells of the arachnoid membrane.
* They may be intracranial (MC), intraorbital, or intra-spinal.
<br clear="all">
 


= Diagnosis =
== Imaging findings ==
* Wide dural based
* Hyperostosis
* Dural tail
* Calcifications
* Homogeneous enhancement 
* Pneumosinus dilatans
* MRI: isointense on T1WI, hypointense on T2WI


[[File:BT SupTentPostFossa OlfGrve 02.jpg|thumb|454x454px]]
== Histopathology ==
[[File:Meningioma - Histopathology .jpg|thumb|500x500px]]
* The tumour cells have features of both syncytial and fibroblastic type forming <mark>whorls</mark> which contain central laminated areas of calcification called <mark>psammoma bodies</mark>.
<br clear="all">
<br clear="all">
= Anterior skull base Meningiomas =
=== Meningioma Grades ===
* Olfactory Groove Meningiomas (OGM) [[File:Nomenclature of anterior skull base meningiomas.jpg|thumb|400x400px|Nomenclature of anterior skull base meningiomas]]
{| class="wikitable" style="width:100%;"
* Planum Sphenoidale Meningiomas
! GRADE I
* Tuberculum Sellae Meningioma (TSM)
! GRADE II
! GRADE III
|-
|  
* Meningothelial meningioma
* Fibrous meningioma
* Transitional meningioma
* Psammomatous meningioma
* Angiomatous meningioma
* Microcystic meningioma
* Secretory meningioma
* Lymphoplasmacyte-rich meningioma
* Metaplastic meningioma
|  
* Atypical meningioma
* Clear cell meningioma
* Chordoid meningioma
|  
* Rhabdoid meningioma
* Papillary meningioma
* Anaplastic (malignant) meningioma
|}


== Comparison of OGM and TSM ==
== Immunohistochemical staining ==
<table class="wikitable"><tr>
* EMA ⊕ in ~80%
    <th width = "20%">Factor</th>
    <th width = "40%">OGM</th>
    <th width = "40%">TSM</th>
  </tr>
  <tr>
    <td>Location</td>
    <td>Cribriform, frontosphenoid suture</td>
    <td>Planum sphenoidale, tuberculum sellae</td>
  </tr>
  <tr>
    <td>Blood supply</td>
    <td>Ant & pos ethmoidals, middle meningeal, ophthalmic (meningeal branch, ACA & ACoA)</td>
    <td>Pos ethmoidal (ACA & ACoA)</td>
  </tr>
  <tr>
    <td>Olfactory nerves</td>
    <td>Superolat</td>
    <td>Inferolat</td>
  </tr>
  <tr>
    <td>Optic nerve/chiasm</td>
    <td>Inferolat</td>
    <td>Superolat</td>
  </tr>
  <tr>
    <td>ACA</td>
    <td>Pos. to posterosuperior</td>
    <td>Posterosuperior</td>
  </tr>
</table>


[[Category:Neuro-Oncology]]
[[Category:Neuro-Oncology]]
[[Category:Meningioma]]
[[Category:Meningioma]]
[[Category:Extrinsic Brain Tumors]]
[[Category:Extrinsic Brain Tumors]]

Latest revision as of 22:57, 4 March 2024

General information

  • Meningiomas are a group of tumors that are believed to originate in meningothelial cells of the arachnoid membrane.
  • They may be intracranial (MC), intraorbital, or intra-spinal.



Diagnosis

Imaging findings

  • Wide dural based
  • Hyperostosis
  • Dural tail
  • Calcifications
  • Homogeneous enhancement
  • Pneumosinus dilatans
  • MRI: isointense on T1WI, hypointense on T2WI

Histopathology

  • The tumour cells have features of both syncytial and fibroblastic type forming whorls which contain central laminated areas of calcification called psammoma bodies.


Meningioma Grades

GRADE I GRADE II GRADE III
  • Meningothelial meningioma
  • Fibrous meningioma
  • Transitional meningioma
  • Psammomatous meningioma
  • Angiomatous meningioma
  • Microcystic meningioma
  • Secretory meningioma
  • Lymphoplasmacyte-rich meningioma
  • Metaplastic meningioma
  • Atypical meningioma
  • Clear cell meningioma
  • Chordoid meningioma
  • Rhabdoid meningioma
  • Papillary meningioma
  • Anaplastic (malignant) meningioma

Immunohistochemical staining

  • EMA ⊕ in ~80%