Meningioma: Difference between revisions

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[[File:Meningioma - Histopathology .jpg|thumb|500x500px]]
[[File:Meningioma - Histopathology .jpg|thumb|500x500px]]
* The tumour cells have features of both syncytial and fibroblastic type forming <mark>whorls</mark> which contain central laminated areas of calcification called <mark>psammoma bodies</mark>.
* The tumour cells have features of both syncytial and fibroblastic type forming <mark>whorls</mark> which contain central laminated areas of calcification called <mark>psammoma bodies</mark>.
== Immunohistochemical staining ==
* EMA ⊕ in ~80%


[[Category:Neuro-Oncology]]
[[Category:Neuro-Oncology]]
[[Category:Meningioma]]
[[Category:Meningioma]]
[[Category:Extrinsic Brain Tumors]]
[[Category:Extrinsic Brain Tumors]]

Revision as of 22:45, 4 March 2024

General information

  • Meningiomas are a group of tumors that are believed to originate in meningothelial cells of the arachnoid membrane.
  • They may be intracranial (MC), intraorbital, or intra-spinal.



Meningioma Grades

GRADE I GRADE II GRADE III
  • Meningothelial meningioma
  • Fibrous meningioma
  • Transitional meningioma
  • Psammomatous meningioma
  • Angiomatous meningioma
  • Microcystic meningioma
  • Secretory meningioma
  • Lymphoplasmacyte-rich meningioma
  • Metaplastic meningioma
  • Atypical meningioma
  • Clear cell meningioma
  • Chordoid meningioma
  • Rhabdoid meningioma
  • Papillary meningioma
  • Anaplastic (malignant) meningioma

Diagnosis

Imaging findings

  • Wide dural based
  • Hyperostosis
  • Dural tail
  • Calcifications
  • Homogeneous enhancement
  • Pneumosinus dilatans
  • MRI: isointense on T1WI, hypointense on T2WI

Histopathology

  • The tumour cells have features of both syncytial and fibroblastic type forming whorls which contain central laminated areas of calcification called psammoma bodies.

Immunohistochemical staining

  • EMA ⊕ in ~80%