Traumatic Brain Injury: Difference between revisions
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| style="width: 15%; vertical-align: top;" | [[BEST-TRIP]] | | style="width: 15%; vertical-align: top;" | [[BEST-TRIP]] | ||
| style="width: 85%; vertical-align: top;" | ✓ ICP monitoring in pts /w severe TBI improves o/c ⇒ Tx | | style="width: 85%; vertical-align: top;" | ✓ ICP monitoring in pts /w severe TBI improves o/c ⇒ ICP focused Tx was not better to care based on CT and Px → routine ICP monitoring does not provide additional benefits for pts o/c <i>(N Engl J Med 2012)</i> | ||
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[[Category:Neurotrauma]] | [[Category:Neurotrauma]] | ||
Revision as of 05:38, 20 July 2024
Key articles
| IMPACT Study | ✓ the value of different prognostic factors in TBI ⇒ the most powerful independent prognostic variables identified were age, GCS motor score, pupil response, and CT finding (Marshall classification), labs (PT & glu) (J Neurotrauma. 2007) |
| DECRA | Efficacy of DC in severe TBI /w refractory ↑ ICP ⇒ DC ↓ ICP & ↓ ICU stay; assoc. /w worse fnx o/c at 6 mn. (N Engl J Med 2011) |
| RESCUEicp | ✓ effectiveness of DC in pts /w TBI & refractory ↑ ICP ⇒ DC ↓ mortality; ↑ risk of severe disability & vegetative state compared to medical Tx alone. (N Engl J Med 2016) |
| BEST-TRIP | ✓ ICP monitoring in pts /w severe TBI improves o/c ⇒ ICP focused Tx was not better to care based on CT and Px → routine ICP monitoring does not provide additional benefits for pts o/c (N Engl J Med 2012) |