Neuro-Oncology

• Molecular markers in Gliomas

• Low Grade Glioma
• High Grade Glioma

Brain Tumor Frequency

• MC intracranial tumors: Brain Metastases (just over 50%).
• Incidence of primary brain tumors: approximately 20-30 per 100,000 in adults and 5 per 100,000 in children.
• About one third of primary brain tumors in adults are malignant, whereas they account for two thirds in childhood.
• Frequency of WHO subgroups and specific tumors is given (information not provided in the text).

Commonest Primary Brain Tumors by WHO Group	Commonest Primary Brain Tumors by Subtype
Meninges (37.6%) Neuroepithelial tissue (29.9%) Sellar region (16.3%) Cranial and spinal nerves (8.1%) Unclassified (5.6%) Lymphoma and hematopoietic (2.1%) Germ cell tumors and cysts (0.4%)	Meningioma (36%) Pituitary tumors (15.5%) Glioblastoma multiforme (15.1%) Nerve sheath tumors (8.1%) Diffuse astrocytoma (2.3%) Primary CNS lymphoma (2%) Ependymal (1.9%) Anaplastic astrocytoma (1.7%) Pilocytic astrocytoma (1.4%) Neuronal and neuronal mixed (1.2%) Oligodendroglioma (1.1%) Oligoastrocytoma (0.9%) Craniopharyngioma (0.8%) Anaplastic oligodendroglioma (0.5%)

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• Pediatric Neuro Oncology