Acute respiratory distress syndrome: Difference between revisions

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(Created page with "* ARDS - acute lung injury w/ PaO2/FIO2 < 200; * def: acute bilateral pul. Infiltrates + hypoxemia w/o ↑ left atrial filling pressure; * causes: sepsis, trauma w/ multiple transfusions, aspiration, diffuse pneumonia; * patho: diffuse alveolar damage w/ hyaline membranes and protein-rich edema fluid in alveoli; * PaO/FiO: ** mild 200-300; ** moderate 100-200; ** severe ≤100); * Tx: PEEP (“lung protective ventilation” = tidal volumes setting - 6 mL/kg...")
 
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{{NoteBox|info}}<strong>Clinical Features of ARDS</strong>
{{NoteBox|info}}<strong>Clinical Features of ARDS</strong>
1. Acute onset
# Acute onset
2. Bilateral infiltrates on frontal chest x-ray
- Bilateral infiltrates on frontal chest x-ray
3. PaO2/FIO2 ≤ 300 mm Hg
- PaO2/FIO2 ≤ 300 mm Hg
4. No evidence of left heart failure or fluid overload
- No evidence of left heart failure or fluid overload
5. The presence of a predisposing condition
- The presence of a predisposing condition
<i>NB! This differs from earlier definitions of ARDS, which required a PaO2/FIO2 ≤ 200 mm Hg for the Dx of ARDS</i><small>MORINIO ICU</small>{{NoteBoxEnd}}
<i>NB! This differs from earlier definitions of ARDS, which required a PaO2/FIO2 ≤ 200 mm Hg for the Dx of ARDS</i> <small>MORINIO ICU</small>{{NoteBoxEnd}}

Revision as of 19:46, 3 March 2024

  • ARDS - acute lung injury w/ PaO2/FIO2 < 200;
  • def: acute bilateral pul. Infiltrates + hypoxemia w/o ↑ left atrial filling pressure;
  • causes: sepsis, trauma w/ multiple transfusions, aspiration, diffuse pneumonia;
  • patho: diffuse alveolar damage w/ hyaline membranes and protein-rich edema fluid in alveoli;
  • PaO/FiO:
    • mild 200-300;
    • moderate 100-200;
    • severe ≤100);
  • Tx: PEEP (“lung protective ventilation” = tidal volumes setting - 6 mL/kg * ideal body weight; MOA: ↑ functional residual capacity)


Clinical Features of ARDS
  1. Acute onset

- Bilateral infiltrates on frontal chest x-ray - PaO2/FIO2 ≤ 300 mm Hg - No evidence of left heart failure or fluid overload - The presence of a predisposing condition

NB! This differs from earlier definitions of ARDS, which required a PaO2/FIO2 ≤ 200 mm Hg for the Dx of ARDS MORINIO ICU