Craniopharyngioma: Difference between revisions

From NeuroWiki
Jump to navigation Jump to search
(Created page with "**Subtypes of craniopharyngioma** Adamantinomatous craniopharyngioma - A craniopharyngioma w/ epithelium that form stellate reticulum, wet karatin and basal pallisades. - Up to 95% of cases of this variant shows CTNNB1 mutations and aberrant nuclear expression of beta- catenin. - Bimodal age distribution: childhood peak age 5–15 years, adult peak age 45–60 years.38 Papillary craniopharyngioma - A craniopharyngioma w/ papillary features. - Occurs in the supratento...")
 
No edit summary
Line 1: Line 1:
**Subtypes of craniopharyngioma**
= Subtypes of craniopharyngioma =


Adamantinomatous craniopharyngioma
== Adamantinomatous craniopharyngioma ==


- A craniopharyngioma w/ epithelium that form stellate reticulum, wet karatin and basal pallisades.
* A craniopharyngioma w/ epithelium that form stellate reticulum, wet keratin and basal palisades.
- Up to 95% of cases of this variant shows CTNNB1 mutations and aberrant nuclear expression of beta- catenin.
* Up to 95% of cases of this variant shows CTNNB1 mutations and aberrant nuclear expression of beta- catenin.
- Bimodal age distribution: childhood peak age 5–15 years, adult peak age 45–60 years.38
* Bimodal age distribution: childhood peak age 5–15 years, adult peak age 45–60 years.38


Papillary craniopharyngioma
== Papillary craniopharyngioma ==


- A craniopharyngioma w/ papillary features.
* A craniopharyngioma w/ papillary features.
- Occurs in the supratentorial compartment or 3rd ventricle.
* Occurs in the supratentorial compartment or 3rd ventricle.
- 81–95% of cases show BRAF V600E mutations.
* 81–95% of cases show BRAF V600E mutations.
- Usually solid, or rarely cystic.
* Usually solid, or rarely cystic.
- Occurs almost exclusively in adults with a mean age of 40–55 years. Epidemiology
* Occurs almost exclusively in adults with a mean age of 40–55 years.  
 
[[Category:Neuro-Oncology]]

Revision as of 01:35, 16 September 2023

Subtypes of craniopharyngioma

Adamantinomatous craniopharyngioma

  • A craniopharyngioma w/ epithelium that form stellate reticulum, wet keratin and basal palisades.
  • Up to 95% of cases of this variant shows CTNNB1 mutations and aberrant nuclear expression of beta- catenin.
  • Bimodal age distribution: childhood peak age 5–15 years, adult peak age 45–60 years.38

Papillary craniopharyngioma

  • A craniopharyngioma w/ papillary features.
  • Occurs in the supratentorial compartment or 3rd ventricle.
  • 81–95% of cases show BRAF V600E mutations.
  • Usually solid, or rarely cystic.
  • Occurs almost exclusively in adults with a mean age of 40–55 years.