Meningioma

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General information

  • Meningiomas are a group of tumors that are believed to originate in meningothelial cells of the arachnoid membrane.
  • They may be intracranial (MC), intraorbital, or intra-spinal.



Meningioma Grades

GRADE I GRADE II GRADE III
  • Meningothelial meningioma
  • Fibrous meningioma
  • Transitional meningioma
  • Psammomatous meningioma
  • Angiomatous meningioma
  • Microcystic meningioma
  • Secretory meningioma
  • Lymphoplasmacyte-rich meningioma
  • Metaplastic meningioma
  • Atypical meningioma
  • Clear cell meningioma
  • Chordoid meningioma
  • Rhabdoid meningioma
  • Papillary meningioma
  • Anaplastic (malignant) meningioma

Diagnosis

Imaging findings

  • Wide dural based
  • Hyperostosis
  • Dural tail
  • Calcifications
  • Homogeneous enhancement
  • Pneumosinus dilatans
  • MRI: isointense on T1WI, hypointense on T2WI

Histopathology

  • The tumour cells have features of both syncytial and fibroblastic type forming whorls which contain central laminated areas of calcification called psammoma bodies.


Meningioma Grades

GRADE I

Immunohistochemical staining

  • EMA ⊕ in ~80%