Intracranial pressure (ICP)
- ICP & Intracranial vol.
- Brain parenchyma: 1400 ml (80% total, 10% solid, 70% tissue water) - CBV: 150 ml (10% total) - CSF: 150 ml (10% total) - Normal ICP: <10-15 mmHg, varies w/ age, position, straining, & coughing (tot. ~1700 ml)
Davson equation
ICP = If * Rout - PSS
- resistance to cerebrospinal fluid outflow (Rout)
- formation of cerebrospinal fluid (If)
- sagittal sinus pressure (PSS)