User contributions for Fmichael1

20 July 2024

• 08:5608:56, 20 July 2024 diff hist +63‎ Traumatic Brain Injury Biomarkers ‎ →‎Clinical Applications and Future Directions
• 08:5608:56, 20 July 2024 diff hist +1‎ Traumatic Brain Injury Biomarkers ‎ →‎Dynamics of TBI Biomarkers
• 08:5508:55, 20 July 2024 diff hist +5,451‎ N Traumatic Brain Injury Biomarkers ‎ Created page with "=== Importance === Biomarkers for TBI are crucial for improving diagnosis, prognosis, treatment, and monitoring of brain injuries, ranging from mild concussions to severe coma. === Clinical Validation === Biomarkers such as Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and Glial Fibrillary Acidic Protein (GFAP) have shown promise in diagnosing TBI. The Banyan BTI test, which measures these biomarkers, received FDA clearance in 2018. === Pathophysiology === Biomarkers refl..."
• 08:5008:50, 20 July 2024 diff hist +45‎ Traumatic Brain Injury ‎No edit summary
• 08:3208:32, 20 July 2024 diff hist −490‎ MediaWiki:Common.css ‎No edit summary current
• 08:3108:31, 20 July 2024 diff hist −6‎ MediaWiki:Common.css ‎No edit summary
• 08:2908:29, 20 July 2024 diff hist +8‎ MediaWiki:Common.css ‎No edit summary
• 08:2608:26, 20 July 2024 diff hist +202‎ MediaWiki:Common.css ‎No edit summary
• 08:1708:17, 20 July 2024 diff hist +3‎ MediaWiki:Common.css ‎No edit summary
• 08:1208:12, 20 July 2024 diff hist +284‎ MediaWiki:Common.css ‎No edit summary
• 07:5307:53, 20 July 2024 diff hist −55‎ Traumatic Axonal Injury ‎ →‎Traumatic Axonal Injury (TAI) Summary current
• 07:5307:53, 20 July 2024 diff hist +648‎ Traumatic Axonal Injury ‎ →‎Diagnosis and Imaging Tag: Visual edit: Switched
• 07:4907:49, 20 July 2024 diff hist +253‎ N File:TAI-B.jpg ‎No edit summary current
• 07:4807:48, 20 July 2024 diff hist +253‎ N File:TAI-A.jpg ‎No edit summary current
• 07:4507:45, 20 July 2024 diff hist +2,285‎ N Traumatic Axonal Injury ‎ Created page with "== Traumatic Axonal Injury (TAI) Summary == === Definition and Mechanism === Traumatic axonal injury (TAI), previously known as diffuse axonal injury (DAI), occurs when shearing forces during acceleration or deceleration cause widespread microscopic axonal damage. This injury often results from rotational acceleration of the head, leading to shear, stretching, and compressive strains that deform brain tissue. TAI can occur without impact forces, although head impacts ty..."
• 07:4207:42, 20 July 2024 diff hist +113‎ Traumatic Brain Injury ‎No edit summary
• 07:4107:41, 20 July 2024 diff hist +68‎ Neurotrauma ‎No edit summary
• 07:3607:36, 20 July 2024 diff hist +4‎ Traumatic Brain Injury ‎ →‎Edema/ICP Elevation
• 07:3407:34, 20 July 2024 diff hist −1‎ Traumatic Brain Injury ‎ →‎Edema/ICP Elevation Tag: Visual edit: Switched
• 07:3307:33, 20 July 2024 diff hist +497‎ Traumatic Brain Injury ‎ →‎Pathophysiology
• 07:2907:29, 20 July 2024 diff hist +111‎ Traumatic Brain Injury ‎ →‎Pathophysiology Tag: Visual edit: Switched
• 07:2707:27, 20 July 2024 diff hist +760‎ N File:The vicious cycle of head injury.jpg ‎No edit summary current
• 07:2607:26, 20 July 2024 diff hist +34‎ Traumatic Brain Injury ‎No edit summary
• 07:1407:14, 20 July 2024 diff hist +2,443‎ N CRASH-2 ‎ Created page with "== CRASH-2 Trial Summary == === Objective === The CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage 2) trial aimed to assess the effects of early administration of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage. === Methods === * '''Design:''' Multicenter, randomized, placebo-controlled trial. * '''Participants:''' 20,211 adult trauma patients with, or at risk of..." current Tag: Visual edit: Switched
• 07:1307:13, 20 July 2024 diff hist +6‎ N File:CRASH2.pdf ‎No edit summary current
• 07:1207:12, 20 July 2024 diff hist +4‎ Traumatic Brain Injury ‎No edit summary
• 07:1107:11, 20 July 2024 diff hist +319‎ Traumatic Brain Injury ‎No edit summary
• 07:0507:05, 20 July 2024 diff hist +74‎ CRASH trial ‎ →‎Reference current
• 07:0407:04, 20 July 2024 diff hist −8‎ CRASH trial ‎ →‎Objective
• 07:0307:03, 20 July 2024 diff hist +31‎ CRASH trial ‎ →‎Reference Tag: Visual edit
• 07:0307:03, 20 July 2024 diff hist +11‎ N File:CRASH-trial.pdf ‎No edit summary current
• 07:0207:02, 20 July 2024 diff hist −9‎ CRASH trial ‎ →‎Outcomes
• 07:0107:01, 20 July 2024 diff hist +2,999‎ N CRASH trial ‎ Created page with "== CRASH-1 Trial Summary == === Objective === The CRASH-1 (Corticosteroid Randomisation After Significant Head Injury) trial aimed to determine whether early administration of corticosteroids reduces death and disability in adults with head injury compared to placebo. === Methods === * '''Design:''' Randomised, placebo-controlled trial with centralised and non-centralised randomised concealed allocation. * '''Blinding:''' Clinicians, patients, and data analysts were bl..."
• 07:0007:00, 20 July 2024 diff hist +336‎ Traumatic Brain Injury ‎No edit summary
• 06:4706:47, 20 July 2024 diff hist +624‎ BEST-TRIP ‎ →‎Conclusion current
• 06:3806:38, 20 July 2024 diff hist −39‎ Traumatic Brain Injury ‎No edit summary
• 06:3706:37, 20 July 2024 diff hist 0‎ Traumatic Brain Injury ‎No edit summary
• 06:3706:37, 20 July 2024 diff hist +47‎ Traumatic Brain Injury ‎No edit summary
• 06:3606:36, 20 July 2024 diff hist −33‎ IMPACT Study ‎ →‎Results current
• 06:3406:34, 20 July 2024 diff hist +303‎ IMPACT Study ‎ →‎Results
• 06:3106:31, 20 July 2024 diff hist +4‎ IMPACT Study ‎ →‎Reference
• 06:3106:31, 20 July 2024 diff hist +143‎ IMPACT Study ‎ →‎Reference Tag: Visual edit: Switched
• 06:3006:30, 20 July 2024 diff hist +14‎ N File:IMPACT-Results.pdf ‎No edit summary current
• 06:2906:29, 20 July 2024 diff hist +6‎ N File:IMPACT.pdf ‎No edit summary current
• 06:2906:29, 20 July 2024 diff hist +2,249‎ N IMPACT Study ‎ Created page with "== IMPACT Study Summary == === Objective === The IMPACT (International Mission for Prognosis and Clinical Trial Design in Traumatic Brain Injury) study aimed to improve the prediction of outcomes in patients with traumatic brain injury (TBI) and to enhance clinical trial design for this population. === Methods === * '''Design:''' A comprehensive analysis based on individual patient data from 11 studies, including three observational studies and eight randomized control..."
• 06:2606:26, 20 July 2024 diff hist +422‎ Traumatic Brain Injury ‎No edit summary
• 05:5805:58, 20 July 2024 diff hist +638‎ BEST-TRIP ‎No edit summary
• 05:5205:52, 20 July 2024 diff hist +103‎ BEST-TRIP ‎No edit summary Tag: Visual edit: Switched
• 05:5105:51, 20 July 2024 diff hist +9‎ N File:BEST-TRIP.pdf ‎No edit summary current
• 05:4905:49, 20 July 2024 diff hist +2,226‎ N BEST-TRIP ‎ Created page with "== BEST-TRIP Trial Summary == === Objective === The BEST-TRIP (Benchmark Evidence from South American Trials: Treatment of Intracranial Pressure) trial aimed to determine whether intracranial pressure (ICP) monitoring improves outcomes in patients with severe traumatic brain injury. === Methods === * '''Design:''' Multicenter, randomized controlled trial. * '''Participants:''' 324 patients aged 13 years or older with severe traumatic brain injury and treated in ICUs in..."