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• 06:01, 20 July 2024 Fmichael1 talk contribs created page CRASH trial (Created page with "== CRASH-1 Trial Summary == === Objective === The CRASH-1 (Corticosteroid Randomisation After Significant Head Injury) trial aimed to determine whether early administration of corticosteroids reduces death and disability in adults with head injury compared to placebo. === Methods === * '''Design:''' Randomised, placebo-controlled trial with centralised and non-centralised randomised concealed allocation. * '''Blinding:''' Clinicians, patients, and data analysts were bl...")