Malformations of Cortical Development

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Categorized into three groups:

Group Characteristics Conditions
Group I Malformations resulting from abnormal proliferation of neuronal and glial cells Microcephaly, macrocephaly, FCDs without and with balloon cells (Taylor dysplasia types IIa and IIb), hemimegalencephaly, tuberous sclerosis, dysembryoplastic neuroepithelial tumors (DNETs), gangliogliomas, gangliocytomas
Group II Malformations resulting from abnormal neuronal migration Lissencephaly, heterotopias
Group III Malformations resulting from abnormal cortical organization Polymicrogyria, schizencephaly, type I FCDs, mild MCDs
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